With the guidance of the International Olympic Committee (IOC) the Olympic Council of Asia (OCA) introduced doping tests at the 1986 10th Asian Games at Seoul, Korea. From September 21st to October 5th, 1986, 585 samples were tested for stimulants, narcotics, anabolic steroids and beta-blockers by gas chromatography-mass spectrometry, high pressure liquid chromatography and fluorescence polarization immuno assay (TDX system by Abbott Lab.). These tests covered about 100 different drugs and another 400 as metabolites. Information about 1000 different drugs were required to interpret the drug screening data properly. The test results and outcome of findings are summarized. 3.2% of the samples were found to contain a banned drug and doping offenders were penalized accordingly.